PRODUCTION OF OXYTETRACYCLINE BY ISOLATED WILD TYPE IRANIAN STREPTOMYCES RIMOSUS

Authors

  • MOHAMMAD ESMAlL ZULFAGHARI the Pharmaceutical Research Center, Daru-Pakhsh Co., P.O. Box 13185-877, Tehran, Islamic Republic of Iran.
  • MORTEZA SATTARI From The Department of Microbiology, Health Science Faculty, Tarbiat Modarres University, Tehran
  • NASRIN MOAZAMI the Biotechnology Center, Iranian Research Organization for Science and Technology, P.O.Box 15815-3338, Tehran
Abstract:

Production of oxytetracycline by an isolated strain of Streptomyces rimosus from Iranian soil was investigated using a special fermentation medium. A comparative study was performed with standard strain PTCC 1144 using the following parameters optimum growth conditions with respect to time, pH, and different amounts of corn steep liquor. Surprisingly, the production yield of the wild strain was 20% more than the standard strain.

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Journal title

volume 8  issue 3

pages  187- 189

publication date 1994-11

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